Based on the original manga series by Kusamizu Bin (story) and Megumi Saburo (art), “FRAGILE” follows the story of Kishi Keiichiro (Nagase Tomoya), a dashingly handsome pathologist who is intensely eccentric and brutally honest, but also holds one of the most brilliant minds. A pathologist is a physician whose job is to determine a diagnosis of disease or cause of death based on an assortment of data, including a patient’s tissue, bodily fluids, organ samples, blood, etc.

Only suit-wearer in a group of white lab coats, Keiichiro comes off as self-centered, antagonistic, and egotistical, yet he is also extremely strong-willed about keeping to his own high standards of morals and medical ethics. This may lead to some unconventional treatments for his patients if it means saving their lives. His unorthodox diagnostic approaches and radical perception typically pit Keiichiro against his own team, his boss and colleagues, but he will do whatever it takes to save his patients.

Oda Naomi (Hirosue Ryoko) dreamed of becoming an art curator, but she currently works in a department store serving VIP clients. Although she has been successful in her career, she feels fed up with her current position. One day, Naomi visits her friend from college Hattori Kanako (Uchida Yuki) and discovers that Kanako has been a victim of domestic violence from her husband Tatsuro (Sato Ryuta). Naomi advises Kanako to divorce Tatsuro, but Kanako is afraid of his reaction and unable to free herself from the situation. Just then, Naomi happens to see a clandestine Chinese who looks exactly like Tatsuro. Naomi soon begins to contrive a perfect scheme to kill Tatsuro.

The protagonist of the drama adaptation is a 30-year-old, unsuccessful sci-fi writer named Hashimoto Jun (Kiriyama Ren). Unable to publish any successful books, Jun lives off through his meager savings. One day, Jun is asked by his editor to write a “love-themed” short story for an online magazine targeted for young readers. Jun refuses at first since he has never written a love story before, but is convinced to take the job. Though the deadline was quickly approaching, Jun was unable to put on paper any words. One day, his childhood friend Murata Keisuke (Kato Shigeaki) stops by for a visit. While talking to Keisuke, Jun remembers an episode from his past which leads him to come up with an idea for his love story titled “Intercept.”

“YAMANEKO (Kamenashi Kazuya) is notoriously elusive, but wherever he shows up, enormous amounts of money gets stolen. Evidence of the audacious crime is left scattered all over the place. In every episode, YAMANEKO the hero thief throws a splash of “rotten justice” in your face.

Pretentiously calling himself a “genius thief,” YAMANEKO is arrogant and acts like he’s the king of the world. Everything he does is bold and daring, but he remains elusive. There is indeed no match for YAMANEKO. He goes by one creed alone—“I will steal but I won’t deprive.”Why does he steal? Just what is he all about? These are the great mysteries of this incredibly entertaining yet highly unpredictable story! YAMANEKO—a new thief and hero emerges!

Mystery writer Arisugawa Arisu (Kubota Masataka), on the other hand, keeps a close eye on Himura’s investigations and writes about them but at times completely misses the point. Not at all the type of guy you’d call dependable, Arisugawa nonetheless professes to be the protector of the clumsy Himura.

Although these two men appear like they have no business being in crime scenes, they mitigate each other’s shortcomings and use their compelling logic to unravel the elaborately woven tricks left behind by the criminals. It’s almost as if Himura and Arisugawa use incredible magical powers to tease out unimaginable truths! Himura stoically tackles bizarre and dark criminal investigations while Arisu’s sense of mission propels him to passionately cover the back of his conflicted and vulnerable buddy. Based on deep trust for each other, theirs is a touching friendship you won’t want to miss!

Daisuke (Katori Shingo) works for a stationery manufacturer and enjoys being single. One day, a fire bell goes off at the apartment he recently bought. Daisuke accuses one of the residents, Hanako (Ueno Juri), who thinks her room is on fire. However, it is actually his father, Youzo (Nishida Toshiyuki), who smoked out Daisuke’s room when he was cooking. To make matters worse, Daisuke’s troublemaking father brought his son-in-law to live all together. His comfortable single life suddenly comes to an end…

30-years-old Kyoko (Ayase Haruka) has a “job”. The story starts with her looking back 20 years to her boarding school of Yoko Gakuen in the mountains. Soccer boy, Tomohiko (Nakagawa Tsubasa), leader among girls, Miwa (Mizuki Sakura), and Kyoko (Suzuki Rio) are all in the same grade. Inspired by the educational philosophy of the principal – Emiko (Aso Yumi), teacher Tatsuko (Ito Ayumi) joins the boarding school staff, but soon finds the school rather strange.

One day, Sumi wakes up and finds herself with the appearance of a 20-year-old. She introduces herself as Sumire and gets another try at youth.

After their marriage, at the cusp of the Meiji era, the Shirooka’s found themselves in dire financial straits, as money changing was no longer a lucrative business anymore. Shinjiro deemed himself not suited to making money and devoted his time to playing the shamisen and pursuing other refined cultural activities. As they neared bankruptcy, Asa decided to turn to coal mining, as that is the much-needed commodity at that time. She set off to Kyushu by herself, to talk to the coal miners to talk about coal supply.

Meanwhile, Hatsu was also married to another prominent family of money changers in Osaka. Facing the same financial difficulties as the Shirooka’s, Hatsu and her husband ran away in the middle of the night, disappearing without a word. One day, Asa bumped into her sister and tried to offer her financial help, but the young couple refused, as they wanted to rebuild their lives using their own capabilities…

The drama depicts the challenges faced by Asa, in a very much male dominated society, and how she overcomes them triumphantly. It also showcases the changes in the Japanese society as the Meiji Restoration slowly swept across the nation

Shibasaki is interrogated over Kido’s sucide, but his boss denies making the phone call regarding Kido. Who made the phone call? Shibasaki Reiji begins to investigate the case, not necessarily to uncover the truth, but to regain his position at the Tokyo Metropolitan Police Department.